ZBED5 Rabbit Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Protein inhibitor of activated STAT

Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates

Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas

Involved in protein trafficking

Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region

and atretic ovary

ZBED5 Rabbit Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Protein inhibitor of activated STATThis gene is unusual in that its coding sequence is mostly derived from Charlie like DNA transposon; however it does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The encoded protein is conserved among the mammalian Laurasiatheria branch. Multiple alternatively spliced variants encoding the same protein have been identified.