p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments IKZF3 encodes a member of

IKZF3 encodes a member of the Ikaros family of zinc-finger proteins

or xeroderma pigmentosum VI (XP6)

or with the TAF15 gene on chromosome 17

which is a potential RNA binding domain

Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors

p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments IKZF3 encodes a member ofThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from