HGK Monoclonal Antibody, 100ul[BT-MCA0675] Cellular Function Assays An important paralog of this

An important paralog of this gene is FRMD3

and thus activated by JNK kinases

This gene lies in close proximity to

NKX3-1 encodes a homeobox-containing transcription factor

This gene| which has also been referred to as GAL3ST2| is different from the GAL3ST2 gene located on chromosome 2 that encodes a related enzyme with distinct tissue distribution and substrate specificities| compared to galactose-3-O-sulfotransferase 3

HGK Monoclonal Antibody, 100ul[BT-MCA0675] Cellular Function Assays An important paralog of thisThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase has been shown to specifically activate MAPK8 JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant negative mutants of MAP3K7 TAK1, MAP2K4 MKK4, and MAP2K7 MKK7, which suggests that this kinase may function through the MAP3K7 MAP2K4 MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. Alternatively