NBK(Phospho Thr33) Polyclonal Antibody, 20ul Peptide Synthesis The protein acts as a

The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family

and maps to human chromosome 12p12

Mutations in this gene are believed to result in congenital ocular defects

multiple sclerosis

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

NBK(Phospho Thr33) Polyclonal Antibody, 20ul Peptide Synthesis The protein acts as aThe protein encoded by this gene shares a critical BH3 domain with other death promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro apoptotic activity, and for interaction with anti apoptotic members of the BCL2 family, and viral survival promoting proteins. Since the activity of this protein is suppressed in the presence of survival promoting proteins, it is suggested as a likely target for anti apoptotic proteins.