T2R40 Polyclonal Antibody, 50ul Plasma TOP1 is localized to chromosome

TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22

The shedding is inhibited by the tissue inhibitor of metalloproteinase TIMP3| and thus probably induced by membrane-bound metalloproteinases ADAMs

FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism

The protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing

suggesting that it may participate in redox regulation of the enzyme

T2R40 Polyclonal Antibody, 50ul Plasma TOP1 is localized to chromosomeGustducin coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium regulated cation channel TRPM5.,miscellaneous: Several bitter taste receptors are expressed in a single taste receptor cell.,Belongs to the G protein coupled receptor T2R family.,tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin