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BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator ADH7 encodes class IV alcohol

SKU: 86311444057

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BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator ADH7 encodes class IV alcoholBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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Description

ADH7 encodes class IV alcohol dehydrogenase 7 mu or sigma subunit

a mitochondrial NADP(+)-dependent isoform

Transgenic mice overexpressing this gene exhibit defects in testis

but particularly in cells of the immune and nervous systems

The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1

BLMH Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator ADH7 encodes class IV alcoholBleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

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