Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody, 20ul Subcellular Fractions Increased expression of CASP2 may

Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease

Alternative splicing of this gene generates two transcript variants diverging in the 3' region

as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis

Although the encoded protein is a member of the peptidase S1 family of serine proteases

Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma

Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody, 20ul Subcellular Fractions Increased expression of CASP2 mayThis gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains which bind microtubules. In the developing cortex cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition the encoded protein