UBP18 Rabbit Polyclonal Antibody, 100ul Cell Dissociation The symbol MIZ1 has also

The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18

as well as multiple transcription activators

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system

Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival

Binding of its ligand

UBP18 Rabbit Polyclonal Antibody, 100ul Cell Dissociation The symbol MIZ1 has alsoThe protein encoded by this gene belongs to the ubiquitin specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin like protein) fusions and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues indicating that this protein is a major