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The impact of GPE on cell proliferation, migration, and survival was examined under basal conditions and in response to a wound-healing assay, relative to two other treatment groups: growth hormone (GH) and GPE + GH groups

Musculoskeletal disorders, including tendinopathy, sarcopenia, osteoarthritis and osteoporosis, represent a major and growing global health burden, with osteoarthritis affecting 32.5 million adults in the United States, osteoporosis affecting 8.4-17.7% of middle-aged and elderly adults and nearly half of skeletal muscle mass being lost by the age of 80 years due to sarcopenia (1,2), particularly in aging populations (3)

Beyond simple cell movement, investigators have explored how TB500 may influence broader patterns of cellular coordination

FIGURE 2 TABLE 1 Commonly used glycyrrhizin preparations

doi: 10.1167/iovs.09-3615 229 CiaowiczMWoniewskiMMurawska-CiaowiczEDzigielP